ea0016s11.2 | Epigenetics in endocrinology | ECE2008
van Heyningen Veronica
The concept of tissue-specific gene expression is familiar to endocrinologists. Starting from the multipotent fertilized egg, selective gene expression is required to generate different tissue and cell types during development. There is generally progressive differentiation of initially dividing, but progressively committed, cells to form mature organs. Timing, size and positioning of organs and the setting up of connections between them all require complex regulation by netwo...